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Note citations are based on reference standards however formatting rules can vary widely between applications and fields of interest or study the specific requirements or preferences of your reviewing publisher classroom teacher institution or organization should be appliedbrain reward systems and abuse 49 hando j topp l hall w amphetamine related harms and treatment preferences of regular amphetamine users in sydney australiadrug addiction is a chronic relapsing brain disorder characterized by a compulsion to take a drug with loss of control over drug intake the hypothesis under discussion here is that chronic drug usetips may 1992 vol13 drugs of abuse anatomy pharmacology and function of reward pathways george f koob drugs of abuse are very powerful reinforcers and even in conditions of limited access where the organism is not dependent these drugs will motivate high rates of opant respondingunfortunately your brain doesnt forget the damage done from using crack long term effects on the brain may include 1 6 structural and functional brain abnormalities worsened memory and attention span compromised dopamine production and activity throughout the brain movement disorders

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